The next 12 months might just redefine the way America thinks about and responds to the opioid epidemic that now claims more than 40,000 lives each year. The nation's biggest drugmakers and distributors face a wave of civil lawsuits that could total tens of billions of dollars in damages.

Thousands of state and local governments, including cities and tribal governments, are demanding that companies like Purdue Pharma, Walmart and Rite-Aid compensate them for the costs of responding to the crisis. They're also pushing companies to reveal far more internal documents, detailing what they knew about the risks of prescription pain medications.

"Our next battle is to get the documents that are being produced made available to the public instead of everything being filed under confidentiality agreements so we can get the facts out," said Joe Rice, an attorney representing local governments suing the drug industry.

How we got here

Some of that internal information could be explosive, changing the way America views the opioid crisis. We know already that in the 1990s there was growing pressure in the health care industry to treat pain more aggressively. Purdue Pharma created a game-changing, long-acting opioid called Oxycontin. The company marketed the drug aggressively to doctors as a safe medication that provided long-term relief.

"In fact, the rate of addiction amongst pain patients who are treated by doctors is much less than one percent," claimed one of the company's advertisements at the time, aimed at convincing skeptical physicians. "These drugs should be used much more than they are for patients in pain."

In their lawsuits, local and state governments claim that dozens of companies — including drugmakers, suppliers and pharmacies — made billions of dollars flooding the U.S. with a variety of prescription pain pills. Critics also say there was a concerted effort by firms to mislead the public and physicians about the dangers.

One of the arguments being made is that pharmacies and drug distributors, including Walgreens, Walmart and CVS, knew that they were selling too many pills, helping to create dangerous levels of addiction and a new black market.

We now also know that the public health risk was severe.

Since 1999, millions of Americans have abused prescription opioids. The federal government reports that more than 130 people now die each day from opioid overdoses, though not all of those drugs were obtained by prescription.

The growing number of people who became addicted also overwhelmed many government agencies, from law enforcement to drug rehab clinics to foster care programs. That's where a lot of these lawsuits come in. Thousands of local and state governments, tribes and cities argue that companies should pick up the tab for battling the epidemic.



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"We are still in the throes of a public health crisis in Summit County," said Greta Johnson, a county official helping to coordinate the response in Akron, Ohio. She argued that the drug industry should be financially responsible for programs designed to ease the suffering in communities like hers. "We're confident the court will see it that way as well."

Paying the price for recovery

Public officials hope for an outcome similar to the massive tobacco settlement of the 1990s. Cigarette-makers have paid out more than $100 billion over the past 20 years to compensate Americans for high rates of illness and public health costs tied to smoking. Some of that money went to programs aimed at helping smokers quit.

Local and state officials say they desperately need that kind of cash settlement to solve this crisis. A lot of the worst opioid abuse is happening in poor, cash-strapped communities. A settlement worth tens of billions of dollars could revolutionize the national response, creating more drug rehab programs, detox beds, and more training for first responders.

Many claims will be tossed

NPR talked with experts who predicted that many of the specific claims in these lawsuits will eventually be tossed out for technical legal reasons. In court filings, companies have argued that local and state governments are the wrong entities to seek financial damages from the epidemic and that statutes of limitations have expired in many jurisdictions.

The industry has also argued that the epidemic was caused by numerous factors, including the actions of government regulators and policymakers, suggesting that firms profiting from opioid sales shouldn't be held liable for misuse. They've also changed their marketing strategies in response to escalating rates of addiction.



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"Earlier this year we ended our practice of promoting opioid medications to prescribers through sales representatives," Purdue Pharma announced on its website in 2018.

But legal scholars following these cases say evidence has emerged already that suggests significant wrongdoing by some of these companies, which could leave them vulnerable financially.

"The judge has made it clear that he wants a settlement ultimately from this, along the lines of the tobacco settlement," said Richard Ausness, a law professor at the University of Kentucky who follows these cases closely. "If that is indeed the way that he feels, he is probably not going to let the defendants off the hook.

He was referring to Judge Dan Polster, whose federal court in Ohio is handling one of the largest test cases, which includes hundreds of consolidated lawsuits. Last month, Polster referred to the opioid crisis as a "man-made plague," but so far no national settlement has materialized.

That sets the stage for big court fights around the country over the next year.
Bloodwork was supposed to be the last step in Isela's application for life insurance. But when she arrived at the lab, her appointment had been canceled.

"That was my first warning," Isela says. She contacted her insurance agent and was told her application was denied because something on her medication list indicated that Isela uses drugs. Isela, a registered nurse who works in an addiction treatment program at Boston Medical Center, scanned her med list. It showed a prescription for the opioid-reversal drug naloxone — brand name Narcan.

"But I'm a nurse, I use it to help people," Isela remembers telling her agent. "If there is an overdose, I could save their life."

That's a message public health leaders aim to spread far and wide. "BE PREPARED. GET NALOXONE. SAVE A LIFE," was the message at the top of a summary advisory from the U.S. surgeon general in April.

But some life insurers consider the use of prescription drugs when reviewing policy applicants. And it can be difficult, some say, to tell the difference between someone who carries naloxone to save others and someone who carries naloxone because they are at risk for an overdose.

Primerica is the insurer Isela says turned her down. (NPR has agreed to use just Isela's first name because she is worried about how this story might affect her ongoing ability to get life insurance.) The company says it can't discuss individual cases. But in a prepared statement, Primerica notes that naloxone has become increasingly available over the counter.

"Now, if a life insurance applicant has a prescription for naloxone, we request more information about its intended use as part of our underwriting process," says Keith Hancock, the vice president for corporate communications. "Primerica is supportive of efforts to help turn the tide on the national opioid epidemic."

After Primerica turned her down, Isela applied to a second life insurer and was again denied coverage. But the second company told her it might reconsider if she obtained a letter from her doctor explaining why she needs naloxone. So, Isela did contact her primary care physician — and then realized that her doctor had not prescribed the drug.

Isela had bought naloxone at a pharmacy. To help reduce overdose deaths, Massachusetts and many other states have established a standing order for naloxone — one prescription that works for everybody. Isela couldn't just give her insurer that statewide prescription; she had to find the doctor who signed it. As it happens, that physician — Dr. Alex Walley — also works at Boston Medical Center.

Walley is an associate professor of medicine at Boston University; he also works in addiction medicine at Boston Medical Center and is the medical director for the Opioid Overdose Prevention Pilot Program at the Massachusetts Department of Public Health.

"We want naloxone to be available to a wide group of people — people who have an opioid use disorder themselves, but also [those in] their social networks and other people in a position to rescue them," Walley says.

He says he's written a half dozen letters for other BMC employees denied life or disability insurance because of naloxone, and that troubles him.

"My biggest concern is that people will be discouraged by this from going to get a naloxone rescue kit at the pharmacy," Walley says. "So this has been frustrating."

The life insurance hassle — and threat of being turned to down -- has discouraged Isela and some of her fellow nurses. She is not carrying a naloxone kit outside the hospital right now because she doesn't want it to show up on her active medication list until the life insurance problem is sorted out.

"So if something were to happen on the street, I don't have one — just because I didn't want another conflict," Isela said.

BMC has alerted the state's Division of Insurance, which has said in a written response that it is reviewing the cases and drafting guidelines for "the reasonable use of drug history information in determining whether to issue a life insurance policy."


But Isela isn't a drug user. And yet, she is being penalized as if she were.

Michael Botticelli, who runs the Grayken Center for Addiction Medicine at BMC, says friends and family members of patients with an addiction must be able to carry naloxone without fear that doing so will send them to the insurance reject pile.

"It's incumbent on all of us to make sure that we try to kind of nip this in the bud," he says, "before it is any more wide-scale."

Botticelli says increased access to naloxone across Massachusetts is one of the main reasons overdose deaths are down in the state. The most recent state report shows 20 fewer fatalities this year compared to last.

Botticelli relayed his concerns in a letter to Dr. Jerome Adams, the U.S. surgeon general, who says he contacted the National Association of Insurance Commissioners. That group says it has not heard of any cases of life insurance applicants being denied because they purchased naloxone.

Adams says it's good to, as Botticelli suggests, nip the problem in the bud.

"Naloxone saves lives," Adams says, "and it is important that all Americans know about the vital role bystanders can play in preventing opioid overdose deaths when equipped with this lifesaving medication."

Isela says the second company that rejected her has agreed to let her reapply, in light of Walley's letter stating that she carries the drug so that she can reverse an overdose. Isela is in the process of reapplying.
They say that acne is part of growing up because your hormones start to change, but when you’ve gone beyond the teenage phase and still have to deal with the embarrassing blemishes on your face, you might want to look for solutions on how to get rid of them and fast. Most of us use creams and ointments to reduce the redness and itching while others prefer to use concealers to hide these blemishes. Although these solutions work, they are only considered as short term fixes. What you need is a treatment that will help get rid of this pesky skin problem and keep it away for good. With that being said, here are 6 remedies that you can start with to get rid of acne.

Increase your fiber intake

One way to banish acne and keep it from coming back is to have more fiber in your body. Fiber can help improve digestion so that all the nutrients from the food that you are eating get absorbed by your body properly. Also, this inhibits inflammation from occurring which is one of the reasons why acne is triggered. Go for foods like chia seeds, sprouts, vegetables, and flax seeds just to name a few.

Use aloe vera

Aloe vera is often the go-to solution for those who are suffering from cuts, bruises, and burns. But did you know that this can also be used to combat acne? Not only does it reduce inflammation, but it has a cooling and soothing effect that can relieve you of the pain and itching. Also, aloe vera can reduce the scars left behind by acne so you can get beautiful skin too.

Reduce sugar intake

Another reason why your skin breaks out in acne is because of eating too much sugar. Eating sweet treats such as chocolates, cakes, and what not can elevate your blood sugar levels and can affect your hormones too. A better option would be to swap your refined sugar with natural sweeteners like stevia and honey instead.

Turmeric can help

Did you know that turmeric is also a useful treatment when it comes to acne breakouts? It’s anti-bacteria and anti-inflammatory properties can fight off the irritation and inflammation on your skin so your acne problem can be reduced significantly. Put turmeric powder in a bowl and add some pineapple juice to it then mix until you create a paste. Apply the mixture on the affected areas afterwards. Leave it on for a few minutes then wash your face thoroughly.

Get some zinc

You should also load up on foods that are rich in zinc as this mineral is needed by your body to support your immune system. This, in turn, can fight off any bacteria that may be triggering your acne. Zinc can also aid in healing your body from any condition and can aid in bodily repair too. Foods like shellfish, baked beans, and fortified cereals are among those foods that contain this important mineral.


Olive oil works too

Another easy remedy to use against acne is olive oil. This is one of the easiest and safest oils available in supermarkets that can fight off acne while nourishing your skin. This is due to the fact that it is packed with vitamins E and K which are known for their healing and repairing of the skin. The iron, potassium, sodium, and calcium in olive oil can also make your skin more elastic and can combat irritation and inflammation too. Get one tablespoon of olive oil and apply gently on the affected areas of your skin. Massage gently until the oil is absorbed. Dip a towel in warm water and wipe the excess oil off. Wash your face with fresh water after five minutes.
Hypotension refers to low blood pressure. It is the opposite of hypertension or high blood pressure. While hypertension is associated with disease, such as cerebrovascular accident or stroke, hypotension is associated with shock, a condition characterized by low body fluid volume. The following are the causes, associated symptoms, and home remedies for hypotension.

Causes

Hypotension has three known causes, among others. According to Medicine Net, the common causes of low blood pressure are low blood volume; heart disease, which yield low cardiac output; and medications, which lower the blood volume in the body. As per the publication, blood tests, cardiac testing, and radiologic examination can be done to determine the nearest cause of the low blood pressure, such as conditions like heart failure or arrhythmias or irregular heart rhythms.

Symptoms

Hypotension is usually accompanied by a number of signs and symptoms. According to Mayo Clinic, these include dizziness or lightheadedness, lack of concentration, blurred vision, thirst, nausea, cold and clammy skin, rapid and shallow breathing, fatigue, and fainting or syncope. As per the publication, it is vital to have a medical consult if the aforementioned signs and symptoms of hypotension.

Home Remedies

While medications that elevate a person’s blood pressure are commercial available for treatment of hypotension, home remedies are also accessible as management for the condition.

Water

Water consumption is a potential remedy for hypotension. Since the problem is reduced fluid volume in the body, drinking glasses of water helps increase the said fluid and blood volume; thus, it helps elevate the blood pressure too. However, it is best to consult a physician prior to increasing oral fluid intake, since it may not be the best intervention in people who have congestive heart failure, in which the heart already has a great workload due to fluid volume excess.

Salt Water

Along with drinking water, salt water also serves as a remedy for low blood pressure. According to Top 10 Home Remedies, salt water aids in elevating the blood pressure, since salt or sodium attracts water. Thus, consuming salt triggers the body to retain fluid. This is through reduced sweating and urination. This way, the body’s blood pressure will rise. As per the publication, the person mixes half teaspoon of salt in a glass of water and drinks it. As an alternative, sports beverages may be consumed.

Slow Position Changes

Position changes can affect a person’s blood pressure. In physiology, sudden position changes cause a sudden drop in blood pressure called orthostatic hypotension. This is accompanied by sudden dizziness after sudden sitting or standing. According to Mayo Clinic, this can be prevented if the person slowly sits or stands. As per the publication, the person should breathe deeply for a few minutes before getting out of bed in the morning. Then, he slowly sits up before standing. Also, the person may sleep with his head slightly elevated to counter the effects of gravity when he wakes up. If dizziness is felt while standing, the person may cross his thighs and squeeze. As per the publication, these movements promote blood flow from the legs to the heart.

Almond milk

Milk is one of the common beverages people have today. According to Food NDTV, it helps counter hypotension. As per the publication, the person soaks five to six almonds overnight and peels them in the morning, makes a paste, and boils them. The resulting preparation is consumed every day to prevent the blood pressure from dropping.

Unmanaged hypotension may lead to shock, which could be deadly, so it has to be managed. It is important to address low blood pressure to the physician for further assessment, planning, implementation, and evaluation.
According to doctors, most cases of heart palpitations are not serious. Some of them can be due to stress, anxiety and exercising, while others can be caused by the diet.

In this article, we will talk about foods that are known to cause heart palpitations.

Before we proceed, let’s get one very important matter perfectly clear: if you are experiencing heart palpitations for the first time and it is accompanied by unusual symptoms such as chest pain, shortness of breath and dizziness, get medical attention right away to have the cause figured out and treated, if necessary.

Do not worry if you’ve been given by your doctor a clean bill of health and still you are experiencing heart palpitations from time to time. Chances are it’s just due to your lifestyle and diet.

Having heart palpitations after eating? Perhaps it’s just due to some of the foods you ate.

Below you will come across some of the foods that are known to cause heart palpitations. Eliminate them from your diet — if you experience no heart palpitations, chances are those foods are the ones to blame!

Cake

A slice of cake is loaded with sugar, which is actually a stimulant. And when you consume cake or anything else that has a lot of sugar in it, then it’s not unlikely for you to experience heart palpitations, among other things.

However, do take note that having low sugar in the blood can cause heart palpitations, too.

The secret is to limit your intake of sugar to prevent heart palpitations due to excessive amounts of it, but do get a little healthy sugar from fruits and complex carbohydrates in order to avoid having low blood sugar levels.

Soda

A couple of reasons exist why consuming soda can leave you with heart palpitations.

First, it is packed with sugar. Just like what’s discussed earlier, too much sugar in the blood can trigger heart palpitations. So should you switch to diet soda to avoid heart palpitations? Don’t, say the experts. That’s because some artificial sweeteners like aspartame are also known to cause heart palpitations.

Second, there is caffeine in soda, and it’s a well-known stimulant.

Coffee

Speaking of caffeine, it’s for certain you will end up with heart palpitations each time you drink coffee, most especially if you’re one of those people who are extremely sensitive to caffeine.

Other than heart palpitations, you may also experience anxiety, hand tremors and nausea because of caffeine.

If you cannot say no to coffee and also do not want to put up with several minutes of having heart palpitations, then limit the amount of coffee you drink per day. Or you may simply switch to decaffeinated coffee.

Chocolate

There is no denying that chocolate tastes wonderful. But do you know what’s not so wonderful about this treat? The heart palpitations that it can cause!

Especially if you like milk chocolate, it’s not unlikely for you to have heart palpitations after eating it because it has sugar and caffeine, both of which are stimulants, just like what’s discussed earlier.

Limit your intake of chocolate and also go for at least 70% cocoa if you cannot completely turn your back on it.

MSG

Some people develop all sorts of unfavorable reactions to MSG, and having heart palpitations is one of those.

If you experience heart palpitations especially after eating junk and Chinese foods, then there is this possibility that you are allergic to MSG, especially high amounts of it.

Aside from heart palpitations, too much MSG may also cause excessive sweating, facial tightness, hot flashes, nausea, tingling sensations and fatigue.

Alcohol

You may experience heart palpitations after consuming alcohol, especially lots and lots of it!

Especially if you’re told by your doctor that you have some sort of problem with your cardiovascular system, it’s a good idea for you to abstain from taking alcohol.

But if you are a healthy individual, consume no more than 2 servings of alcohol a day if you’re a male and no more than 1 serving of alcohol a day if you’re a woman to avoid problems.
It’s common knowledge that loading up on foods that are rich in vitamin C is an effective way to strengthen the immune system. Everyone is striving to boost their immunity as it helps in lowering the risk of getting infections and certain diseases. Did you know that exercising also helps make the immune system strong?

Continue reading if you like to know which exercises are very good at toughening up your immunity. Don’t forget to share this article later on to get your family and friends introduced to these immune-strengthening exercises, too!

Yes, scientists agree that exercising can in fact make a person’s immune system better at doing its job, and that is getting the body safeguarded from disease-causing microorganisms that like to attack. When you exercise, you actually activate certain immune cells and also lower inflammation that can weaken the immune system.

So should you start exercising a lot to make yourself impervious to anything that we don’t want to end up with, from the common cold to certain types of cancer? Don’t, say the experts!

While exercising is a great way to have your immune system bolstered, too much of it can actually result in the complete opposite, and that is a weakened immune system. Instead of lowering your risk of infections and diseases, excessive exercising can actually leave you more susceptible to ending up in poor health.

Here are some of the exercises that you should go for if you want to enjoy a stronger immune system:


Yoga

It’s true that yoga consists of nothing but all sorts of different weird poses, but it’s actually a wonderful form of exercise for having the immune system reinforced. That’s because yoga is very good at relieving stress, which is something that can cause a person’s immunity to deteriorate considerably, experts say.

Attending a yoga class or watching yoga tutorials posted on the internet allows you to incorporate one of the best immune-strengthening exercises into your life.


Tai Chi

Actually, tai chi is an ancient form of Chinese martial arts. These days, however, it is a very popular form of exercise perfect for everyone no matter the age or fitness level.

The slow movements of tai chi is said to help facilitate the lymphatic system’s task of ridding the body of toxins. The more toxin-free you are, the stronger your immune system gets. Besides, tai chi is also a phenomenal remedy for stress and anxiety, both of which can have a negative impact on a person’s immunity.


Walking

Did you know that something as simple as walking for at least 20 minutes a day is already considered as an excellent form of exercise? It’s actually regarded as the best because it is safe and low impact, too. Even though it’s not as challenging as most other forms of exercise, walking is still an effective strengthener of the immune system.

It’s a good idea to walk outside because exposure to the sun is also good for one’s immunity as well as mood. However, avoid walking in the sun between 10 in the morning and 4 in the afternoon.

Bicycling

Just in case you get bored of walking, give riding a bicycle a try. It’s another form of low impact exercise that is easy on the joints, and it’s also fun and can be done with a bunch of your friends.

A form of aerobic exercise just like walking, bicycling reduces stress which can be blamed for a weakened immune system. It also strengthens the heart and lungs, helping to make the removal of toxins and microbes in the body more efficient.

Because it is enjoyable, it’s easy to add bicycling to your everyday routine.


Strength Training

Experts say that building muscles also helps make the immune system stronger. Muscles need to store amino acids, the building blocks of protein, for maintenance. What’s so nice about those amino acids is they assist in the production of immune cells that zap bacteria, viruses and fungi that like to invade our bodies.

No, you don’t have to lift those super heavy barbells that power lifters use. The use of resistance bands and lightweight dumbbells is usually enough for you to build muscles and have your immunity strengthened.